Intra-arterial lidocaine therapy via the middle meningeal artery for migraine headache: Theory, current practice and future directions

Marco Mancuso-Marcello; Adnan I Qureshi; Christos Nikola; Irina Stoian; YiFan Jia; Danial Saeed; Pervinder Bhogal

doi:10.1177/15910199231195470

Intra-arterial lidocaine therapy via the middle meningeal artery for migraine headache: Theory, current practice and future directions

Interv Neuroradiol. 2023 Aug 13:15910199231195470. doi: 10.1177/15910199231195470. Online ahead of print.

Authors

Marco Mancuso-Marcello¹, Adnan I Qureshi², Christos Nikola³, Irina Stoian³, YiFan Jia⁴, Danial Saeed³, Pervinder Bhogal¹

Affiliations

¹ Interventional Neuroradiology, Barts Health NHS Trust, London, UK.
² Zeenat Qureshi Stroke Institute and Department of Neurology, University of Missouri, Columbia, MO, USA.
³ Stroke, Barts Health NHS Trust, London, UK.
⁴ Imperial College School of Medicine, Imperial College London, London, UK.

PMID: 37574789
DOI: 10.1177/15910199231195470

Abstract

Recent developments in neurointerventional research have seen the emergence of the middle meningeal artery (MMA) as an effective conduit for intra-arterial (IA) therapy for a number of pathologies. Here, we review the anatomical, pathophysiological and experimental basis for utilisation of the MMA for IA treatment of migraine headache. We explore the in-human case literature for the treatment of headaches with IA lidocaine and discuss considerations and challenges for future research.

Keywords: Migraine disorders; headache; injections; intra-arterial.

Publication types

Review