Planning and effectiveness of intensive rehabilitation as a treatment for a patient with neurosarcoidosis: A case report

Medicine (Baltimore). 2023 Aug 11;102(32):e34519. doi: 10.1097/MD.0000000000034519.

Abstract

Introduction: Neurosarcoidosis tends to prolong the duration of treatment and may result in a decline in physical function requiring rehabilitation. Because of a rare disease, the adjustment of oral steroid dosage, which is the cornerstone of treatment, is highly dependent on professional experience in general. Therefore, the number of hospitals that can perform dosage adjustment is very limited, and it is difficult to provide concurrent intense rehabilitation at the same hospital over a long period of time, and there are no reports that mention this.

Patient concerns: A 49-year-old man, who presented with impaired consciousness, dysphagia and right hemiplegia, was diagnosed with neurosarcoidosis based on a previous diagnosis of sarcoidosis, laboratory test results, and clinical symptoms. High-dose oral steroid therapy was initiated and he was transferred to our rehabilitation hospital for progressive disuse approximately 2 months after the disease onset.

Diagnoses: This case was diagnosed as "probable" neurosarcoidosis.

Interventions: The steroid dose was not reduced during rehabilitation treatment in our hospital considering the risk of relapse of the primary disease due to steroid reduction. His training regimen focused on minimum activities of daily living was performed, and its effectiveness was determined during approximately 60 days after the initiation of rehabilitation.

Outcomes: Two months after admission, he was independently eating, transferring, and toileting under supervision. He was discharged home 3 months after admission.

Lessons: Intensive rehabilitation can be one of the effective comprehensive treatment strategy for patients with neurosarcoidosis. On the other hand, since there is no consensus treatment method, the duration of rehabilitation and goal setting should be adjusted based on an understanding of the characteristics of the disease and the overall treatment plan.

Publication types

  • Case Reports

MeSH terms

  • Activities of Daily Living
  • Central Nervous System Diseases* / complications
  • Central Nervous System Diseases* / drug therapy
  • Humans
  • Male
  • Middle Aged
  • Sarcoidosis* / complications
  • Sarcoidosis* / diagnosis
  • Sarcoidosis* / drug therapy
  • Treatment Outcome

Supplementary concepts

  • Neurosarcoidosis