Epithelioid haemangioendothelioma-a rare cause of right pleural effusion and multiple primary nodules: Case report & review of the literature

Ryan Bashir Mohamed; Monica Shehata; William Gorman; Abdullah AlShammari; Silviu Buderi; Simon Jordan

doi:10.1177/20542704231188569

Epithelioid haemangioendothelioma-a rare cause of right pleural effusion and multiple primary nodules: Case report & review of the literature

JRSM Open. 2023 Aug 7;14(8):20542704231188569. doi: 10.1177/20542704231188569. eCollection 2023 Aug.

Authors

Ryan Bashir Mohamed¹, Monica Shehata¹, William Gorman², Abdullah AlShammari¹, Silviu Buderi¹, Simon Jordan¹

Affiliations

¹ Department of Thoracic Surgery, The Royal Brompton Hospital, London, UK.
² University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK.

Abstract

Pulmonary epithelioid haemangioendothelioma (PEH) is a rare vascular neoplasm. The thoracic manifestation of this disorder is identified via three major imaging patterns, namely multiple primary nodules, diffuse infiltrative pleural thickening, and multiple pulmonary reticulonodular opacities. The commonest pattern of presentation is bilateral multiple nodules. Diagnosis is based on histopathological findings and verified by positive immunochemistry staining. Patients with PEH are usually asymptomatic. We report the case of a 51-year-old female who presented to our facility with a five-month history of cough, pleural nodularity, and pleural effusion. She underwent surgical washout with right pleural biopsies that showed a malignant epithelioid tumor with features of epithelioid haemangioendothelioma (EH). A CXR after treatment did not demonstrate a residual pleural effusion.

Keywords: Epithelioid haemangioendothelioma; case report; literature review.

Publication types

Case Reports