Research progress of nanomaterial drug delivery in tumor targeted therapy

Peng Zhang; Guihua Ye; Guofeng Xie; Jie Lv; Xianhai Zeng; Wei Jiang

doi:10.3389/fbioe.2023.1240529

Research progress of nanomaterial drug delivery in tumor targeted therapy

Front Bioeng Biotechnol. 2023 Jul 24:11:1240529. doi: 10.3389/fbioe.2023.1240529. eCollection 2023.

Authors

Peng Zhang¹, Guihua Ye², Guofeng Xie³, Jie Lv⁴, Xianhai Zeng¹, Wei Jiang³

Affiliations

¹ Department of Otorhinolaryngology, Longgang Otorhinolaryngology Hospital & Shenzhen Key Laboratory of Otorhinolaryngology, Shenzhen Institute of Otorhinolaryngology, Shenzhen, China.
² Shanghai Ninth People's Hospital Hainan Branch, Hainan Western Central Hospital, Danzhou, China.
³ Affiliated Cancer Hospital and Institute of Guangzhou Medical University, Guangzhou, China.
⁴ School of Computer Science and Engineering, Yulin Normal University, Yulin, China.

Abstract

Cancer is one of the most lethal diseases in human society, and its incidence is gradually increasing. However, the current tumor treatment often meets the problem of poor efficacy and big side effects. The unique physical and chemical properties of nanomaterials can target the delivery of drugs to tumors, which can improve the therapeutic effect while reducing the damage of drugs to normal cells. This makes nanomaterials become a hot topic in the field of biomedicine. This review summarizes the recent progress of nanomaterials in tumor targeted therapy.

Keywords: drug delivery; nanomaterials; targeted therapy; tumor; tumorigenic factors.

Publication types

Review

Grants and funding

The present study was supported in part by the Guangdong Basic and Applied Basic Research Foundation (2021A1515010970); Shenzhen Innovation of Science and Technology Commission (Nos. JCYJ20210324132407019, LGKCYLWS2022002, LGKCYLWS2021000027, and LGKCYLWS2020099); Shenzhen Key Medical Discipline Construction Fund (No. SZXK039).