Long COVID-19 Cardiac Complications Are Associated With Autoimmunity to Cardiac Self-Antigens Sufficient to Cause Cardiac Dysfunction

Circulation. 2023 Aug 8;148(6):504-507. doi: 10.1161/CIRCULATIONAHA.122.062672. Epub 2023 Aug 7.

Marco Cremonesi^#¹, Arianna Felicetta^#², Francesco Cannata^#^{2

3}, Simone Serio^#^{2

3}, Jasper J P van Beek^#⁴, Sara Bombace^#², Ilaria My^#², Veronica Zanon⁴, Chiara Catalano^{1

3}, Vasiliki Papadopoulou^{1

3}, Lorenzo Monti^{5

3}, Mauro Chiarito^{2

3}, Giulio Stefanini^{2

3}, Cristina Panico^{2

3}, Marco Francone^{5

3}, Enrico Lugli⁴, Marinos Kallikourdis^#^{1

3}, Gianluigi Condorelli^#^{2

3}

¹ Adaptive Immunity Laboratory (M. Cremonesi, C.C., V.P., M.K.), Rozzano, Milan, Italy.
² Cardio Center (A.F., F.C., S.S., S.B., I.M., M. Chiarito, G.S., C.P., G.C.), Rozzano, Milan, Italy.
³ Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy (F.C., S.S., C.C., V.P., L.M., M. Chiarito, G.S., C.P., M.F., M.K., G.C.).
⁴ Laboratory of Translational Immunology (J.J.P.v.B., V.Z., E.L.), Rozzano, Milan, Italy.
⁵ Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Humanitas Research Hospital (L.M., M.F.), Rozzano, Milan, Italy.

^# Contributed equally.

No abstract available

Keywords: autoantibodies; autoantigens; autoimmunity; heart diseases; post-acute COVID-19 syndrome.

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