Preoperative detection of functional somatostatin receptors in a patient with an insulinoma

Kohei Oguni; Shinnosuke Fukushima; Yukichika Yamamoto; Kou Hasegawa; Hideharu Hagiya; Naoko Inoshita; Fumio Otsuka

doi:10.1002/ccr3.7771

Preoperative detection of functional somatostatin receptors in a patient with an insulinoma

Clin Case Rep. 2023 Aug 2;11(8):e7771. doi: 10.1002/ccr3.7771. eCollection 2023 Aug.

Authors

Kohei Oguni¹, Shinnosuke Fukushima¹, Yukichika Yamamoto¹, Kou Hasegawa¹, Hideharu Hagiya¹, Naoko Inoshita², Fumio Otsuka¹

Affiliations

¹ Department of General Medicine Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan.
² Department of Pathology Moriyama Memorial Hospital Tokyo Japan.

Abstract

Octreotide is used in patients with insulinomas to treat hypoglycemia, and somatostatin receptor (SSTR) 2 expression is important for its efficacy. We report a case of insulinoma in a 50-year-old woman that responded to an octreotide test, showed accumulation in somatostatin scintigraphy, and was positive for SSTR2A on immunostaining.

Keywords: Insulinoma; octreotide test; somatostatin receptor; somatostatin scintigraphy.

Publication types

Case Reports