Detection mechanism and the outlook of metal-organic frameworks for the detection of hazardous substances in milk

Guijian Tan; Sanying Wang; Jialin Yu; Jiahao Chen; Donghui Liao; Miao Liu; Alireza Nezamzadeh-Ejhieh; Ying Pan; Jianqiang Liu

doi:10.1016/j.foodchem.2023.136934

Detection mechanism and the outlook of metal-organic frameworks for the detection of hazardous substances in milk

Food Chem. 2024 Jan 1:430:136934. doi: 10.1016/j.foodchem.2023.136934. Epub 2023 Jul 26.

Authors

Guijian Tan¹, Sanying Wang², Jialin Yu³, Jiahao Chen³, Donghui Liao³, Miao Liu³, Alireza Nezamzadeh-Ejhieh⁴, Ying Pan⁵, Jianqiang Liu⁶

Affiliations

¹ The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, China; Guangdong Provincial Key Laboratory of Research and Development of Natural Drugs, and School of Pharmacy, Guangdong Medical University, Guangdong Medical University Key Laboratory of Research and Development of New Medical Materials, Dongguan 523808, China.
² Department of Pain, Dalang Hospital, Dongguan 523770, China.
³ Guangdong Provincial Key Laboratory of Research and Development of Natural Drugs, and School of Pharmacy, Guangdong Medical University, Guangdong Medical University Key Laboratory of Research and Development of New Medical Materials, Dongguan 523808, China.
⁴ Chemistry Department, Shahreza Branch, Islamic Azad University, Shahreza, Isfahan, Iran. Electronic address: arnezamzadeh@iaush.ac.ir.
⁵ The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, China; Guangdong Provincial Key Laboratory of Research and Development of Natural Drugs, and School of Pharmacy, Guangdong Medical University, Guangdong Medical University Key Laboratory of Research and Development of New Medical Materials, Dongguan 523808, China. Electronic address: panying@gdmu.edu.cn.
⁶ The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan 523808, China; Guangdong Provincial Key Laboratory of Research and Development of Natural Drugs, and School of Pharmacy, Guangdong Medical University, Guangdong Medical University Key Laboratory of Research and Development of New Medical Materials, Dongguan 523808, China. Electronic address: jianqiangliu2010@126.com.

PMID: 37542961
DOI: 10.1016/j.foodchem.2023.136934

Abstract

Milk has a high nutritional value. However, milk is easily contaminated in the production, processing, and storage processes, which harms consumers' health. Therefore, the harmful substances' detection in milk is important. Metal-organic frameworks (MOFs) have proven high potential in food safety detection due to their unique porous structure, large effective surface area, large porosity, and structural tunability. This article systematically describes the detection mechanism of fluorescence, electrochemical, colorimetric, and enzyme-linked immunosorbent assay based on MOFs. The progress of the application of MOFs in the detection of antibiotics, harmful microorganisms and their toxins, harmful ions, and other harmful substances in milk in recent years is reviewed. The structural tunability of MOFs enables them to be functionalized, giving the ability to be applied to different detection methods or substances. Therefore, MOFs can be used as an advantageous sensing material for detecting harmful substances in the complex environment of milk.

Keywords: Detection; Hazardous substances; MOFs; Mechanism; Milk.

Publication types

Review

MeSH terms

Animals
Anti-Bacterial Agents
Colorimetry
Hazardous Substances
Metal-Organic Frameworks*
Milk*

Substances

Metal-Organic Frameworks
Hazardous Substances
Anti-Bacterial Agents