Identification and Classification of Lungs Focal Opacity Using CNN Segmentation and Optimal Feature Selection

Comput Intell Neurosci. 2023 Jul 26:2023:6357252. doi: 10.1155/2023/6357252. eCollection 2023.

Abstract

Lung cancer is one of the deadliest cancers around the world, with high mortality rate in comparison to other cancers. A lung cancer patient's survival probability in late stages is very low. However, if it can be detected early, the patient survival rate can be improved. Diagnosing lung cancer early is a complicated task due to having the visual similarity of lungs nodules with trachea, vessels, and other surrounding tissues that leads toward misclassification of lung nodules. Therefore, correct identification and classification of nodules is required. Previous studies have used noisy features, which makes results comprising. A predictive model has been proposed to accurately detect and classify the lung nodules to address this problem. In the proposed framework, at first, the semantic segmentation was performed to identify the nodules in images in the Lungs image database consortium (LIDC) dataset. Optimal features for classification include histogram oriented gradients (HOGs), local binary patterns (LBPs), and geometric features are extracted after segmentation of nodules. The results shown that support vector machines performed better in identifying the nodules than other classifiers, achieving the highest accuracy of 97.8% with sensitivity of 100%, specificity of 93%, and false positive rate of 6.7%.

MeSH terms

  • Databases, Factual
  • Diagnosis, Computer-Assisted / methods
  • Humans
  • Lung / diagnostic imaging
  • Lung Neoplasms* / diagnostic imaging
  • Tomography, X-Ray Computed* / methods