What Is the Role of Lymph Node Resections in Small Islet Tumors?

Alexandra Gangi; Cristina R Ferrone

doi:10.1016/j.yasu.2023.06.001

What Is the Role of Lymph Node Resections in Small Islet Tumors?

Adv Surg. 2023 Sep;57(1):47-58. doi: 10.1016/j.yasu.2023.06.001.

Authors

Alexandra Gangi¹, Cristina R Ferrone²

Affiliations

¹ Gastrointestinal Tumor Program, Division of Surgical Oncology, Department of Surgery, Cedars-Sinai Medical Center, 8700 Beverly Boulevard North Tower, Suite 8215, Los Angeles, CA 90048, USA. Electronic address: Alexandra.gangi@cshs.org.
² Department of Surgery, Cedars-Sinai Medical Center, 8700 Beverly Boulevard North Tower, Suite 8215, Los Angeles, CA 90048, USA.

PMID: 37536861
DOI: 10.1016/j.yasu.2023.06.001

Abstract

Well-differentiated nonfunctional pancreatic neuroendocrine tumors are often indolent neoplasms without lymph node (LN) metastasis at diagnosis. Patients with PNETs that are functional or >2 cm should have surgical resection as per the standard of care. However, in appropriately selected patients with NF PNETs <2 cm who are at low risk of LN metastasis, the extent of surgery and lymphadenectomy could be limited.

Keywords: Islet cell tumors; Lymphadenectomy; Pancreatic neuroendocrine tumors; Surgery.

Publication types

Review

MeSH terms

Humans
Lymph Node Excision
Lymph Nodes / pathology
Lymph Nodes / surgery
Neuroectodermal Tumors, Primitive* / pathology
Neuroectodermal Tumors, Primitive* / surgery
Neuroendocrine Tumors* / diagnosis
Neuroendocrine Tumors* / pathology
Neuroendocrine Tumors* / surgery
Pancreatectomy
Pancreatic Neoplasms* / pathology
Retrospective Studies