Circulation of influenza C virus of C/Sao Paulo/378/82 lineage among pediatric acute respiratory cases, Shandong, China

Hong Zhou; Jiansheng Liu; Linlin Li; Ju Sun; Qingjuan Wei; Yu Huan; Michael J Carr; Yuhai Bi; Weifeng Shi

doi:10.1016/j.virol.2023.109855

Circulation of influenza C virus of C/Sao Paulo/378/82 lineage among pediatric acute respiratory cases, Shandong, China

Virology. 2023 Oct:587:109855. doi: 10.1016/j.virol.2023.109855. Epub 2023 Jul 27.

Authors

Hong Zhou¹, Jiansheng Liu², Linlin Li¹, Ju Sun³, Qingjuan Wei², Yu Huan⁴, Michael J Carr⁵, Yuhai Bi⁶, Weifeng Shi⁷

Affiliations

¹ School of Clinical and Basic Medical Sciences, Shandong First Medical University & Shandong Academy of Medical Sciences, Ji'nan, 250117, China; Key Laboratory of Emerging Infectious Diseases in Universities of Shandong, School of Clinical and Basic Medical Sciences, Shandong First Medical University and Shandong Academy of Medical Sciences, Tai'an, 271000, China.
² Taian Maternal and Child Health Hospital, Tai'an, 271000, China.
³ CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Center for Influenza Research and Early-warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), Chinese Academy of Sciences, Beijing, China; College of Veterinary Medicine, Shanxi Agriculture University, Jinzhong, 030031, China.
⁴ CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Center for Influenza Research and Early-warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), Chinese Academy of Sciences, Beijing, China; University of Chinese Academy of Sciences, Beijing, 100049, China.
⁵ National Virus Reference Laboratory, School of Medicine, University College Dublin, Dublin, Ireland; International Collaboration Unit, Research Center for Zoonosis Control, Hokkaido University, N20 W10 Kita-ku, Sapporo, 001-0020, Japan.
⁶ CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Center for Influenza Research and Early-warning (CASCIRE), CAS-TWAS Center of Excellence for Emerging Infectious Diseases (CEEID), Chinese Academy of Sciences, Beijing, China; College of Veterinary Medicine, Shanxi Agriculture University, Jinzhong, 030031, China; University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: beeyh@im.ac.cn.
⁷ Department of Infectious Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China; Shanghai Institute of Virology, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. Electronic address: shiwf@ioz.ac.cn.

PMID: 37536021
DOI: 10.1016/j.virol.2023.109855

Abstract

Influenza C virus (ICV) was identified in five pediatric acute respiratory cases in Shandong. Co-infection with other respiratory viruses was detected in four of these cases. Two ICV genomes were obtained and clustered in the S1-sublineage of C/Sao Paulo/378/82, indicating that genetically diverse ICV strains have been circulating in mainland China.

Keywords: Acute respiratory infection; Co-infection; Genome; Influenza C virus.