Evaluation and Management of Hypertensive Disorders of Pregnancy

Kidney360. 2023 Oct 1;4(10):1512-1525. doi: 10.34067/KID.0000000000000228.

Abstract

Hypertensive disorders of pregnancy complicate up to 10% of pregnancies and remain the major cause of maternal and neonatal morbidity and mortality. Hypertensive disorders of pregnancy can be classified into four groups depending on the onset of hypertension and the presence of target organ involvement: chronic hypertension, preeclampsia, gestational hypertension, and superimposed preeclampsia on chronic hypertension. Hypertension during pregnancy is associated with a higher risk of cardiovascular disease and kidney failure. Early diagnosis and proper treatment for pregnant women with hypertension remain a priority since this leads to improved maternal and fetal outcomes. Labetalol, nifedipine, methyldopa, and hydralazine are the preferred medications to treat hypertension during pregnancy. In this comprehensive review, we discuss the diagnostic criteria, evaluation, and management of pregnant women with hypertension.

Publication types

  • Review
  • Research Support, N.I.H., Intramural

MeSH terms

  • Antihypertensive Agents / therapeutic use
  • Female
  • Humans
  • Hypertension, Pregnancy-Induced* / diagnosis
  • Hypertension, Pregnancy-Induced* / drug therapy
  • Infant, Newborn
  • Labetalol* / therapeutic use
  • Nifedipine / therapeutic use
  • Pre-Eclampsia* / diagnosis
  • Pre-Eclampsia* / drug therapy
  • Pregnancy

Substances

  • Antihypertensive Agents
  • Labetalol
  • Nifedipine