Balloon-occluded Esophageal Varices Obliteration Versus Ligation for the Management of F2 Esophageal Varices: A Randomized Controlled Trial

Xuecan Mei; Qianqian Zhang; Fuming Zhang; Jing Jin; Zhuang Zeng; Derun Kong

doi:10.1097/SLE.0000000000001209

Balloon-occluded Esophageal Varices Obliteration Versus Ligation for the Management of F2 Esophageal Varices: A Randomized Controlled Trial

Surg Laparosc Endosc Percutan Tech. 2023 Oct 1;33(5):456-462. doi: 10.1097/SLE.0000000000001209.

Authors

Xuecan Mei¹, Qianqian Zhang, Fuming Zhang, Jing Jin, Zhuang Zeng, Derun Kong

Affiliation

¹ Department of Gastroenterology, the First Affiliated Hospital of Anhui Medical University, Key Laboratory of Digestive Diseases of Anhui Province, Hefei, Anhui, China.

PMID: 37523518
DOI: 10.1097/SLE.0000000000001209

Abstract

Aim: To compare balloon-occluded esophageal varices obliteration (BEVO) with esophageal variceal ligation (EVL) in the management of cirrhotic patients with type F2 esophageal varices (F2-EVs).

Materials and methods: A total of 157 patients with F2-EVs were randomly assigned to either BEVO (n=79) or EVL (n=78) group in the prospective study between July 2021 and December 2021. Primary outcomes included recurrence and eradication rates. Secondary outcomes included rebleeding rate, and procedural complications.

Results: The recurrence rate of EVs was notably lower in the BEVO group than in the EVL group (3.80% vs. 21.79%; P =0.001). The rate of complete eradication in the BEVO group was significantly higher than that of the EVL group (96.20% vs. 74.36%; P <0.001). The incidence of rebleeding in the BEVO group was markedly lower than that of the EVL group (7.59% vs. 20.51%; P =0.02). There was a higher incidence of transient dysphagia in the EVL group than in the BEVO group (10.26% vs. 1.27%; P =0.015).

Conclusions: BEVO exerted an effective treatment option for F2-EVs.