Research hotspots and trends on neuromyelitis optica spectrum disorders: insights from bibliometric analysis

Xin Chen; Jun Xiao; Luo-Qi Zhou; Wen-Xiang Yu; Man Chen; Yun-Hui Chu; Ke Shang; Gang Deng; Wen-Hui Song; Chuan Qin; Deng-Ji Pan; Dai-Shi Tian

doi:10.3389/fimmu.2023.1135061

Research hotspots and trends on neuromyelitis optica spectrum disorders: insights from bibliometric analysis

Front Immunol. 2023 Jul 13:14:1135061. doi: 10.3389/fimmu.2023.1135061. eCollection 2023.

Authors

Xin Chen¹, Jun Xiao¹, Luo-Qi Zhou¹, Wen-Xiang Yu¹, Man Chen¹, Yun-Hui Chu¹, Ke Shang¹, Gang Deng¹, Wen-Hui Song¹, Chuan Qin¹, Deng-Ji Pan¹, Dai-Shi Tian¹

Affiliation

¹ Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Abstract

Neuromyelitis optica spectrum disorders (NMOSD) are demyelinating diseases of the central nervous system, have drawn the attention of many researchers due to the relapsing courses and cumulative disability. A first bibliometric analysis of NMOSD was conducted to identify the research hotspots and emerging trends. Articles relevant to NMOSD published in the core collection of Web of Science were retrieved and analyzed through visualized analysis using CiteSpace and VOSviewer, focusing on annual publication trends, countries, institutions, authors, journals, and keywords. The analysis showed that over the past 30 years, publications related to NMOSD had shown steady growth with slight fluctuations. The United States played an important part in this field, with the highest outputs and the greatest number of citations. Research hotspots of NMOSD had gradually shifted from the definition, biomarkers, and diagnostic criteria to diagnosis and treatment, particularly immunotherapy. This bibliometric analysis provides researchers with a theoretical basis for studying NMOSD and offers guidance for future research directions.

Keywords: CiteSpace; VOSviewer; bibliometric analysis; neuromyelitis optica spectrum disorders; research hotspots.

Publication types

Review

Grants and funding

This work was funded by the National Natural Science Foundation of China (Grants 82071380, 81873743, and 82271341), and Tongji Hospital (HUST) Foundation for Excellent Young Scientists (Grant No. 2020YQ06).