The First Case in Japan of Fulminant Myocarditis Due to Multisystem Inflammatory Syndrome in Children (MIS-C) That Required Mechanical Circulatory Support

Int Heart J. 2023;64(4):783-788. doi: 10.1536/ihj.23-116.

Abstract

Multisystem inflammatory syndrome in children (MIS-C) is a novel hyperinflammatory syndrome that is associated with severe acute respiratory syndrome coronavirus 2 infections. Reports describing the mechanical circulatory support (MCS) and myocardial biopsy for fulminant myocarditis due to MIS-C are limited.A 13-year-old male patient with MIS-C underwent treatment, including immunosuppressive therapy and MCS devices, and managed to recover from pulseless electrical activity cardiac arrest.This is the first patient in Japan with MIS-C who required MCS devices in Japan. Appropriate and immediate treatment with immunosuppressive therapy and MCS devices is important.

Keywords: Endomyocardial biopsy; Impella; SARS-CoV-2.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • COVID-19* / complications
  • Child
  • Heart Arrest* / complications
  • Humans
  • Japan
  • Male
  • Myocarditis* / complications
  • Myocarditis* / diagnosis
  • Systemic Inflammatory Response Syndrome / diagnosis
  • Systemic Inflammatory Response Syndrome / etiology
  • Systemic Inflammatory Response Syndrome / therapy

Supplementary concepts

  • pediatric multisystem inflammatory disease, COVID-19 related