CRISPR/Cas9 boosts wheat yield by reducing brassinosteroid signaling

Sunny Ahmar; Damian Gruszka

doi:10.1016/j.tibs.2023.07.005

CRISPR/Cas9 boosts wheat yield by reducing brassinosteroid signaling

Trends Biochem Sci. 2023 Nov;48(11):917-919. doi: 10.1016/j.tibs.2023.07.005. Epub 2023 Jul 28.

Authors

Sunny Ahmar¹, Damian Gruszka²

Affiliations

¹ Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia, Jagiellonska 28, 40-032 Katowice, Poland.
² Institute of Biology, Biotechnology and Environmental Protection, Faculty of Natural Sciences, University of Silesia, Jagiellonska 28, 40-032 Katowice, Poland. Electronic address: damian.gruszka@us.edu.pl.

PMID: 37517884
DOI: 10.1016/j.tibs.2023.07.005

Abstract

A modern green revolution is needed to ensure global food security. Recently, Song et al. reported a new strategy to create high-yielding, semi-dwarf wheat varieties with improved nitrogen-use efficiency by inhibiting brassinosteroid (BR) signaling through clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein9 (Cas9)-mediated knockout of the ZnF-B gene encoding a zinc-finger RING-type E3 ligase.

Keywords: CRISPR/Cas9; brassinosteroid; nitrogen-use efficiency; semi-dwarfism; wheat; yield.