Leveraging microbiome information for animal genetic improvement

Trends Genet. 2023 Oct;39(10):721-723. doi: 10.1016/j.tig.2023.07.004. Epub 2023 Jul 27.

Abstract

There is growing evidence that the microbiome influences host phenotypic variation. Incorporating information about the holobiont - the host and its microbiome - into genomic prediction models may accelerate genetic improvements in farmed animal populations. Importantly, these models must account for the indirect effects of the host genome on microbiome-mediated phenotypes.

Keywords: genomic prediction; hologenomics; microbiability; microbiome breeding.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Genome / genetics
  • Genomics
  • Microbiota* / genetics
  • Models, Genetic
  • Phenotype