Advances in 3D Bioprinting: Techniques, Applications, and Future Directions for Cardiac Tissue Engineering

Catherine A Wu; Yuanjia Zhu; Y Joseph Woo

doi:10.3390/bioengineering10070842

Advances in 3D Bioprinting: Techniques, Applications, and Future Directions for Cardiac Tissue Engineering

Bioengineering (Basel). 2023 Jul 16;10(7):842. doi: 10.3390/bioengineering10070842.

Authors

Catherine A Wu¹, Yuanjia Zhu^{1

2}, Y Joseph Woo^{1

2}

Affiliations

¹ Department of Cardiothoracic Surgery, Stanford University, Stanford, CA 94305, USA.
² Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.

Abstract

Cardiovascular diseases are the leading cause of morbidity and mortality in the United States. Cardiac tissue engineering is a direction in regenerative medicine that aims to repair various heart defects with the long-term goal of artificially rebuilding a full-scale organ that matches its native structure and function. Three-dimensional (3D) bioprinting offers promising applications through its layer-by-layer biomaterial deposition using different techniques and bio-inks. In this review, we will introduce cardiac tissue engineering, 3D bioprinting processes, bioprinting techniques, bio-ink materials, areas of limitation, and the latest applications of this technology, alongside its future directions for further innovation.

Keywords: bio-inks; biomaterials; bioprinting; cardiac tissue engineering.

Publication types

Review

Grants and funding

This research received no external funding.