Research Progress on Porcine Reproductive and Respiratory Syndrome Virus NSP7 Protein

Huawei Li; Qin Luo; Huiyuan Jing; Yuzhen Song; Weili Kong; Mengmeng Zhao; Qingge Zhu

doi:10.3390/ani13142269

Research Progress on Porcine Reproductive and Respiratory Syndrome Virus NSP7 Protein

Animals (Basel). 2023 Jul 11;13(14):2269. doi: 10.3390/ani13142269.

Authors

Huawei Li¹, Qin Luo², Huiyuan Jing³, Yuzhen Song³, Weili Kong⁴, Mengmeng Zhao², Qingge Zhu²

Affiliations

¹ College of Food and Bioengineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450047, China.
² Department of Veterinary Medicine, School of Life Science and Engineering, Foshan University, Foshan 528000, China.
³ College of Veterinary Medicine, Henan University of Animal Husbandry and Economy, Zhengzhou 450047, China.
⁴ Gladstone Institutes of Virology and Immunology, University of California, San Francisco, CA 94158, USA.

Abstract

Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious and severe infectious disease caused by the PRRS virus (PRRSV). PRRS is characterized by reproductive disorders in sows and respiratory dysfunction in pigs. Non-structural protein 7 (NSP7) is one of the most conserved functional proteins in PRRSV, and it plays an important role in viral replication and humoral immune responses in infected hosts. This review discusses the biological characteristics of NSP7 to provide theoretical support for its application in PRRS diagnosis, novel vaccine design, and therapeutic drug development.

Keywords: NSP7; PRRS; PRRSV; biological characteristics; research progress.

Publication types

Review

Abstract

Publication types

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