Comparative gene expression profiling reveals differential expression of GATA3 and Wnt signaling in juxtaglomerular cell tumors compared to renal glomus tumors

Hum Pathol. 2023 Sep:139:138-140. doi: 10.1016/j.humpath.2023.07.004. Epub 2023 Jul 20.

Authors

Farhad Kosari¹, Carlos Sosa², Irem Kilic³, Andres M Acosta³, Aditya Raghunathan², Loren Herrera Hernandez², Vidit Sharma⁴, John C Cheville², Sounak Gupta⁵

Affiliations

¹ Department of Molecular Medicine, Mayo Clinic, Rochester, MN, 55905, USA.
² Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA.
³ Department of Pathology, Indiana University, Indianapolis, IN, 46202, USA.
⁴ Department of Urology, Mayo Clinic, Rochester, MN, 55905, USA.
⁵ Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55905, USA. Electronic address: Gupta.Sounak@mayo.edu.

PMID: 37478920
DOI: 10.1016/j.humpath.2023.07.004

No abstract available

Keywords: GATA3; Glomus tumor; Juxtaglomerular cell tumor; RNAseq.

Publication types

Comparative Study
Letter

MeSH terms

Biomarkers, Tumor / genetics
GATA3 Transcription Factor / metabolism
Gene Expression Profiling
Glomus Tumor*
Humans
Kidney / pathology
Kidney Neoplasms* / pathology
Wnt Signaling Pathway / genetics

Substances

Biomarkers, Tumor
GATA3 protein, human
GATA3 Transcription Factor