Hyperbaric oxygen therapy as an adjunct to corticosteroid treatment in sudden sensorineural hearing loss: a retrospective study

Piotr H Skarzynski; Aleksandra Kolodziejak; Elżbieta Gos; Magdalena B Skarzynska; Natalia Czajka; Henryk Skarzynski

doi:10.3389/fneur.2023.1225135

Hyperbaric oxygen therapy as an adjunct to corticosteroid treatment in sudden sensorineural hearing loss: a retrospective study

Front Neurol. 2023 Jul 5:14:1225135. doi: 10.3389/fneur.2023.1225135. eCollection 2023.

Authors

Piotr H Skarzynski^{1

2

3}, Aleksandra Kolodziejak¹, Elżbieta Gos¹, Magdalena B Skarzynska^{3

4

5}, Natalia Czajka¹, Henryk Skarzynski⁶

Affiliations

¹ Department of Teleaudiology and Screening, World Hearing Center, Institute of Physiology and Pathology of Hearing, Kajetany/Warsaw, Poland.
² Heart Failure and Cardiac Rehabilitation Department, Faculty of Medicine, Medical University of Warsaw, Warsaw, Poland.
³ Institute of Sensory Organs, Kajetany/Warsaw, Poland.
⁴ Center of Hearing and Speech Medincus, Kajetany/Warsaw, Poland.
⁵ Pharmacy Department, Department of Pharmacotherapy and Pharmaceutical Care, Medical University of Warsaw, Warsaw, Poland.
⁶ Otorhinolaryngosurgery Clinic, World Hearing Center, Institute of Physiology and Pathology of Hearing, Kajetany/Warsaw, Poland.

Abstract

Background: A retrospective clinical study was conducted to test the impact of including hyperbaric oxygen therapy in the treatment of patients with sudden sensorineural hearing loss (SSNHL).

Materials and methods: A total of 63 adult patients with sudden sensorineural hearing loss diagnosed between 2015 and 2023 were divided into two groups: 36 patients treated with intratympanic glucocorticoid and orally administered glucocorticoid who also underwent hyperbaric oxygen therapy and 27 patients treated with intratympanic glucocorticoid and prolonged orally administered glucocorticoid (without hyperbaric oxygen therapy). An audiological evaluation was performed using pure-tone audiometry.

Results: Average hearing gain as measured by pure tone average was 12.5 dB HL (+/- 19.9 dB HL) in the patients treated with steroids combined with HBOT, and was 14.1 dB HL (+/- 17.9 dB) in the patients treated with steroids alone. Successful treatment (complete recovery or marked improvement) was observed in 27.8% of the patients in the first group and in 25.5% in the second group. There was no statistically significant difference between the groups.

Conclusion: Both groups of patients-those treated with glucocorticoids and those treated with glucocorticoids and HBOT-had similar hearing outcomes. A prospective, controlled, and randomized study would provide more reliable knowledge about the efficacy of HBOT in treating SSNHL.

Keywords: HBOT; glucococorticoids; hearing loss; hyperbaric oxygen therapy; sudden sensorineural hearing loss.