Background: Posttraumatic stress disorder (PTSD) and depression are associated with increased risk for cardiovascular disease (CVD), which is the leading cause of death and disability worldwide. Epidemiological studies have revealed these illnesses to be highly comorbid, particularly among women. In the current study, we explored associations between indices of cardiovascular health, PTSD, and depression among a sample of trauma-exposed individuals assigned female at birth.Methods: Participants were N = 49 individuals without CVD who reported lifetime Criterion A trauma exposure. Blood pressure (BP), heart rate (HR), and high-frequency heart rate variability (HF-HRV) were collected during a 5-minute resting period. Symptoms of CVD (e.g. extremity pain and swelling, shortness of breath), PTSD, and depression were assessed, along with an exploratory measure of anhedonia.Results: Trauma exposure was positively correlated with systolic BP (r = .32, p = .029) and diastolic BP (r = .30, p = .040). The number of reported CVD symptoms was positively correlated with symptoms of PTSD (r = .41, p = .004), depression (r = .40, p = .005) and anhedonia (r = .38, p = .007). CVD symptoms were also significantly associated with PTSD (β = .41, t = 2.43, p = .023), depression (β = .40, t = 2.76, p = .009), and anhedonia (β = .38, t = 2.51, p = .017) after controlling for age and trauma exposure. These associations were not moderated by HF-HRV in our sample.Conclusions: Our results support the association between PTSD and depressive symptoms and worse cardiovascular functioning among an often-overlooked population that is particularly vulnerable to these illnesses. Future studies should investigate residual impacts of PTSD and depression treatment on CVD risk among trauma-exposed individuals, particularly women.
Antecedentes: El trastorno de estrés postraumático (TEPT) y la depresión están asociados con un mayor riesgo de enfermedad cardiovascular (ECV), que es la principal causa de muerte y discapacidad en todo el mundo. Los estudios epidemiológicos han revelado que estas enfermedades son altamente comórbidas, particularmente entre las mujeres. En el estudio actual, exploramos las asociaciones entre los índices de salud cardiovascular, el TEPT y la depresión en una muestra de personas asignadas como mujeres al nacer, expuestas a traumas.
Métodos: Los participantes fueron N =
Resultados: La exposición al trauma se correlacionó positivamente con la PA sistólica (r = .32, p = .029) y la PA diastólica (r =
Conclusiones: Nuestros resultados respaldan la asociación entre TEPT, síntomas depresivos y peor funcionamiento cardiovascular entre una población a menudo ignorada que es particularmente vulnerable a estas enfermedades. Los estudios futuros deberían investigar los impactos residuales del TEPT y el tratamiento de la depresión en el riesgo de ECV entre las personas expuestas al trauma, en particular las mujeres.
背景：创伤后应激障碍 (PTSD) 和抑郁与全世界死亡和残疾主要原因——心血管疾病 (CVD) 的风险增加有关。流行病学研究表明，这些疾病是高度共病的，尤其是在女性中。在本研究中，我们在出生时被指定为女性的创伤暴露个体样本中探索了心血管健康指数、PTSD 和抑郁之间的关联。
方法：参与者是 49 名没有 CVD 的人，他们报告了终身标准 A 创伤暴露。在 5 分钟的休息期间收集血压 (BP)、心率 (HR) 和高频心率变异性 (HF-HRV)。评估了 CVD（例如，肢体疼痛和肿胀、呼吸急促）、PTSD 和抑郁症状，以及快感缺乏的探索性测量。
结果：创伤暴露与收缩压 (r = .32, p = .029) 和舒张压 (r = .30, p = .040) 呈正相关。报告的 CVD 症状数量与 PTSD（r = .41，p = .004）、抑郁（r = .40，p = .005）和快感缺失（r = .38，p = .007）症状呈正相关 。在控制了年龄和创伤暴露后，CVD 症状也与 PTSD (β = .41, t =
结论：在一个对相关疾病易感却经常被忽视的群体中，我们的结果支持了 PTSD 与抑郁症状和心血管功能恶化之间的关联。未来的研究应该考查 PTSD 和抑郁治疗对创伤暴露个体（尤其是女性）CVD 风险的残余影响。
Keywords: Anhedonia; Blood pressure; Cardiovascular; Depression; PTSD; TEPT; anhedonia; cardiovascular; depresión; presión arterial; 心血管; 快感缺失; 抑郁; 血压.
Trauma exposure and PTSD are associated with depression and cardiovascular disease (CVD) risk.We explored cardiovascular health, PTSD, and depression among 49 trauma-exposed individuals assigned female at birth.Trauma exposure positively correlated with blood pressure.CVD symptoms were positively correlated with PTSD, depression, and anhedonia.Associations were not moderated by heart rate variability.