The article summarize the most important changes regarding the management of valvular heart disease, which have been made in the ESC Guidelines 2021. Based on the randomized clinical study data, which were recently published, the most frequent changes were done in terms of the choice of mode of intervention in the aortic and mitral valves as well as in the management of the antithrombotic therapy.
Keywords: aortic regurgitation; aortic stenosis; guidelines; mitral regurgitation; mitral stenosis; percutaneous valve intervention; prosthetic heart valves; tricuspid regurgitation; tricuspid stenosis; valve disease; valve surgery; valvular heart disease.