Potential biomarkers: Predicting post-treatment viral rebound in rhesus macaques

Chenbo Yang; Jing Xue

doi:10.1016/j.xcrm.2023.101118

Potential biomarkers: Predicting post-treatment viral rebound in rhesus macaques

Cell Rep Med. 2023 Jul 18;4(7):101118. doi: 10.1016/j.xcrm.2023.101118.

Authors

Chenbo Yang¹, Jing Xue²

Affiliations

¹ NHC Key Laboratory of Human Disease Comparative Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
² NHC Key Laboratory of Human Disease Comparative Medicine, Beijing Key Laboratory for Animal Models of Emerging and Remerging Infectious Diseases, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China; Center for AIDS Research, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100730, China. Electronic address: xuejing@cnilas.org.

Abstract

In this issue of Cell Reports Medicine, Aid and colleagues define peripheral blood biomarkers, which predict viral rebound after antiretroviral therapy (ART) discontinuation in SIV-infected rhesus macaques treated early with ART, providing insights into potential HIV cure strategies.¹.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Animals
Biomarkers
HIV Infections* / drug therapy
Macaca mulatta
Simian Acquired Immunodeficiency Syndrome* / drug therapy
Simian Immunodeficiency Virus*
Virus Replication

Substances

Biomarkers