Vitamin D levels in patients with seborrheic dermatitis

Rev Assoc Med Bras (1992). 2023 Jul 17;69(7):e20230022. doi: 10.1590/1806-9282.20230022. eCollection 2023.

Abstract

Objective: Seborrheic dermatitis is a common papulosquamous skin disease with unknown pathogenesis. The aim of our study was to determine the serum level of 25-hydroxy vitamin D in patients with seborrheic dermatitis SD.

Methods: A total of 53 patients and 60 healthy controls were included in the study. Serum vitamin D, calcium, phosphorus, and parathormone levels were measured in the patient and control groups, and a comparison was made between the two groups regarding these parameters.

Results: Severe vitamin D deficiency was more frequent among patients with seborrheic dermatitisSD compared to controls (52.8 vs. 25.8%, p=0.003). In patients with severe vitamin D deficiency, seborrheic dermatitis SD was detected more frequently at an early age (p=0048) and in women (p=0.015). No correlation was found between the seborrheic dermatitis skin involvement site and vitamin D level.

Conclusion: The fact that vitamin D levels decreased in patients with seborrheic dermatitis SD and patients with severe vitamin D deficiency develop seborrheic dermatitis SD earlier suggests that the low levels of vitamin D are related to seborrheic dermatitis.

MeSH terms

  • Dermatitis, Seborrheic* / pathology
  • Female
  • Humans
  • Skin / pathology
  • Vitamin D
  • Vitamin D Deficiency* / complications
  • Vitamins

Substances

  • Vitamin D
  • Vitamins