Catheter related atrial thrombus caused by Abiotrophia defectiva: A case series and review of literature

J Vasc Access. 2023 Jul 19:11297298231188926. doi: 10.1177/11297298231188926. Online ahead of print.

Abstract

Catheter related atrial thrombus (CRAT) is a devastating complication associated with tunneled hemodialysis catheter. Abiotrophia defectiva is a rare fastidious pathogen implicated predominantly in culture negative infective endocarditis. Here we report three cases of CRAT in maintenance hemodialysis patients with variable clinical presentation caused by Abiotrophia defectiva. Video assisted thoracoscopic retrieval of atrial thrombus is a novel technique which is scarcely reported in medical literature for surgical management of large atrial thrombus. Our cases were managed by timely administration of antibiotics and anticoagulants followed by surgical retrieval of atrial thrombus with removal of tunneled dialysis catheter. This case series illustrates the importance of prompt diagnosis, appropriate anticoagulation with antibiotics, and mini-invasive surgical removal of atrial thrombus for the management of CRAT.

Keywords: Abiotrophia defectiva; CRAT; Catheter related atrial thrombus; tunneled hemodialysis catheter.