Relationship between pulse pressure and body mass index in active-duty Royal Thai Army personnel in Thailand

Boonsub Sakboonyarat; Jaturon Poovieng; Tanatip Sangkool; Sethapong Lertsakulbunlue; Kanlaya Jongcherdchootrakul; Phutsapong Srisawat; Mathirut Mungthin; Ram Rangsin

doi:10.1186/s12872-023-03390-w

Relationship between pulse pressure and body mass index in active-duty Royal Thai Army personnel in Thailand

BMC Cardiovasc Disord. 2023 Jul 18;23(1):361. doi: 10.1186/s12872-023-03390-w.

Authors

Boonsub Sakboonyarat¹, Jaturon Poovieng², Tanatip Sangkool¹, Sethapong Lertsakulbunlue³, Kanlaya Jongcherdchootrakul¹, Phutsapong Srisawat¹, Mathirut Mungthin⁴, Ram Rangsin⁵

Affiliations

¹ Department of Military and Community Medicine, Phramongkutklao College of Medicine, Bangkok, 10400, Thailand.
² Department of Medicine, Phramongkutklao College of Medicine, Bangkok, 10400, Thailand.
³ Department of Pharmacology, Phramongkutklao College of Medicine, Bangkok, 10400, Thailand.
⁴ Department of Parasitology, Phramongkutklao College of Medicine, Bangkok, 10400, Thailand.
⁵ Department of Military and Community Medicine, Phramongkutklao College of Medicine, Bangkok, 10400, Thailand. r_rangsin@yahoo.com.

Abstract

Background: Elevated pulse pressure (PP) is a robust independent predictor of cardiovascular diseases. The relationship between PP and body mass index (BMI) was presented in a few studies. However, the findings were inconsistent. Therefore, the aim of the present study is to identify the association between elevated PP and BMI using a large sample of active-duty Royal Thai Army (RTA) personnel.

Methods: A cross-sectional study was conducted through the use of the dataset obtained from the annual health examination database of RTA personnel in Thailand in 2022. BMI 25.0-29.9 kg/m² was classified as obesity I, whereas BMI ≥ 30.0 kg/m² was classified as obesity II. Elevated PP was defined as PP ≥ 50 mmHg. Multivariable linear regression and log-binomial regression models were utilized for determining the association between elevated PP and BMI.

Results: A total of 62,113 active-duty RTA personnel were included in the study. The average BMI was 25.4 ± 3.8 kg/m², while the average PP was 50.1 ± 11.2 mmHg. Compared to individuals with normal weight, the [Formula: see text] coefficients of PP and BMI were 1.38 (95% CI: 1.15-1.60) and 2.57 (95% CI: 2.25-2.88) in individuals with obesity I and obesity II, respectively. Effect modification by high blood pressure (BP) on the association between elevated PP and BMI was observed. Among participants with normal BP, in comparison with BMI of 18.5-22.9 kg/m², the adjusted prevalence ratio (PR) for elevated PP was 1.23 (95% CI: 1.19-1.28) and 1.41 (95% CI: 1.35-1.48) in those with obesity I and obesity II, respectively. Meanwhile, among individuals with high BP, the adjusted PR for elevated PP was 1.05 (95% CI: 1.01-1.08) and 1.09 (95% CI: 1.06-1.13) in those with obesity I and obesity II, respectively.

Conclusion: PP was positively associated with BMI in active-duty RTA personnel. High BP was the modifier of the association between PP and BMI. A weaker association between elevated PP and BMI was observed among RTA personnel with high BP.

Keywords: Body mass index; High blood pressure; Pulse pressure; Royal Thai Army; Thailand.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Blood Pressure / physiology
Body Mass Index
Cross-Sectional Studies
Humans
Hypertension* / diagnosis
Hypertension* / epidemiology
Military Personnel*
Obesity / diagnosis
Obesity / epidemiology
Southeast Asian People
Thailand / epidemiology