Objective: Risk stratification is challenging in patients with acute ST segment elevation myocardial infarction (STEMI) after primary percutaneous coronary intervention (PCI). We investigated the prognostic value of a novel score system combining leucocyte and platelet counts (COL-P) scores for in-hospital and long-term adverse outcomes.
Design: This was a retrospective cohort study of patients with STEMI.
Setting: First Affiliated Hospital of Xinjiang Medical University.
Participants: A total of 854 STEMI patients with primary PCI were included in this study from November 2009 and December 2015.
Primary and secondary outcome measures: Major adverse cardiovascular events (MACEs).
Methodology: The patients were divided into three groups according to the COL-P scores (0, 1 and 2). Cox regression analysis was used to investigate the relation between adverse outcomes and the COL-P score in patients with STEMI.
Results: A total of 44 patients died in hospital, and 99 within 3-year follow-up after discharge. The in-hospital and 3-year mortality and MACEs were higher in patients with higher COL-P score. Multivariable Cox regression indicated COL-P score was independently associated with long-term mortality (COL-P 1 vs COL-P 0: HR 2.07, 95% CI 1.016 to 5.567, p=0.005; COL-P 2 vs COL-P 0: HR 5.02, 95% CI 1.990 to 9.041, p<0.001).
Conclusion: The COL-P score was a useful risk system for stratifying high-risk patients with STEMI after primary PCI.
Keywords: Coronary heart disease; Coronary intervention; Myocardial infarction.
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