Uncontrolled Diabetes Mellitus Predicts Post-COVID-19 Fibrosis

J Assoc Physicians India. 2023 Jul;71(7):11-12. doi: 10.59556/japi.71.0288.

Abstract

Introduction: Post-coronavirus 2019 (COVID-19) complications are now well-recognized and may involve multiple organs. Post-COVID-19 pulmonary fibrosis is one of the serious long-term consequences of COVID-19 infection, and the risk factors for its development largely remain unidentified.

Aims and objectives: The study aimed to evaluate the clinical and radiological profile of post COVID-19 patients with diagnosed diabetes mellitus (DM).

Materials and methods: All the patients attending the post-COVID-19 respiratory care center over a period of 1 year who were diagnosed with cases of DM were evaluated for residual clinical symptoms and radiological changes and glycosylated hemoglobin (HbA1c) levels were measured from their blood samples.

Results: A total of 50 patients were enrolled in this observational cross-sectional study. Most patients were males in the age group of 45-60 years. Approximately 74% of patients had uncontrolled DM. Patients with uncontrolled DM had a higher probability of having a severe disease with an odds ratio (OR) of 7.30 (0.85, 62.42, and confidence interval (CI) 95%) and were more likely to have fibrotic abnormalities on computed tomography (CT) chest with OR of 3.38 (0.87, 16.86, and CI 95%).

Conclusion: Uncontrolled diabetes predisposes to the development of post-COVID-19 fibrosis, so physicians should be more vigilant while managing these patients.

Publication types

  • Observational Study

MeSH terms

  • COVID-19* / complications
  • Diabetes Mellitus* / epidemiology
  • Female
  • Fibrosis
  • Humans
  • Male
  • Middle Aged
  • Risk Factors
  • SARS-CoV-2