Application of Nondegradable Synthetic Materials for Tendon and Ligament Injury

Macromol Biosci. 2023 Dec;23(12):e2300259. doi: 10.1002/mabi.202300259. Epub 2023 Jul 19.

Abstract

Tendon and ligament injuries, prevalent requiring surgical intervention, significantly impact joint stability and function. Owing to excellent mechanical properties and biochemical stability, Nondegradable synthetic materials, including polyethylene terephthalate (PET) and polytetrafluoroethylene (PTFE), have demonstrated significant potential in the treatment of tendon and ligament injuries. These above materials offer substantial mechanical support, joint mobility, and tissue healing promotion of the shoulder, knee, and ankle joint. This review conclude the latest development and application of nondegradable materials such as artificial patches and ligaments in tendon and ligament injuries including rotator cuff tears (RCTs), anterior cruciate ligament (ACL) injuries, and Achilles tendon ruptures.

Keywords: ligament injuries; nondegradable; synthetic materials; tendon injuries; tissue scaffold.

Publication types

  • Review

MeSH terms

  • Humans
  • Ligaments
  • Rotator Cuff Injuries*
  • Tendon Injuries* / therapy
  • Tendons
  • Wound Healing