Effects of dietary nitrate supplementation on peak power output: Influence of supplementation strategy and population

Rachel Tan; Marissa N Baranauskas; Sean T Karl; Joaquin Ortiz de Zevallos; Ren-Jay Shei; Hunter L Paris; Chad C Wiggins; Stephen J Bailey

doi:10.1016/j.niox.2023.06.004

Effects of dietary nitrate supplementation on peak power output: Influence of supplementation strategy and population

Nitric Oxide. 2023 Sep 1:138-139:105-119. doi: 10.1016/j.niox.2023.06.004. Epub 2023 Jul 10.

Authors

Rachel Tan¹, Marissa N Baranauskas², Sean T Karl³, Joaquin Ortiz de Zevallos⁴, Ren-Jay Shei⁵, Hunter L Paris³, Chad C Wiggins⁶, Stephen J Bailey⁷

Affiliations

¹ Department of Sports Medicine, Pepperdine University, Malibu, CA, 90263, USA. Electronic address: rachel.tan@pepperdine.edu.
² Department of Human Physiology & Nutrition, University of Colorado, Colorado Springs, CO, 80918, USA.
³ Department of Sports Medicine, Pepperdine University, Malibu, CA, 90263, USA.
⁴ Department of Kinesiology, University of Virginia, Charlottesville, VA, 22904, USA.
⁵ Indiana University Alumni Association, Indiana University, Bloomington, IN, 47408, USA.
⁶ Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN, USA.
⁷ School of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, LE11 3TU, UK.

PMID: 37438201
DOI: 10.1016/j.niox.2023.06.004

Abstract

Increasing evidence indicates that dietary nitrate supplementation has the potential to increase muscular power output during skeletal muscle contractions. However, there is still a paucity of data characterizing the impact of different nitrate dosing regimens on nitric oxide bioavailability and its potential ergogenic effects across various population groups. This review discusses the potential influence of different dietary nitrate supplementation strategies on nitric oxide bioavailability and muscular peak power output in healthy adults, athletes, older adults and some clinical populations. Effect sizes were calculated for peak power output and absolute and/or relative nitrate doses were considered where applicable. There was no relationship between the effect sizes of peak power output change following nitrate supplementation and when nitrate dosage when considered in absolute or relative terms. Areas for further research are also recommended including a focus on nitrate dosing regimens that optimize nitric oxide bioavailability for enhancing peak power at times of increased muscular work in a variety of healthy and disease populations.

Keywords: Beetroot; Ergogenic aid; Nitric oxide; Skeletal muscle.

Publication types

Published Erratum