Noninvasive treatment of psoriasis and skin rejuvenation using an akermanite-type narrowband emitting phosphor

Luminescence. 2023 Sep;38(9):1668-1677. doi: 10.1002/bio.4554. Epub 2023 Jul 27.

Abstract

Psoriasis is a noncontagious, long-lasting skin infection that affects many people around the world. Numerous therapeutic artificial treatments are available for the treatment of psoriasis, such as photodynamic therapy using broadband ultraviolet (UV) lamps, which have harmful effects on human skin. Similarly, the natural healing systems such as sunlight have a higher risk of sunburn and can cause dangerous forms of skin cancer. Significant light emission of a specific wavelength (in the UV range), and phosphor-based devices demonstrate the effectiveness of treating psoriasis without damaging the skin. Gd3+ -doped calcium magnesium silicate [Ca2 MgSi2 O7 :Gd3+ ,(CMS:Gd3+ )] phosphor is one of the ideal phosphors that emit specific narrow UV wavelengths for curing psoriasis and is in great demand in the field of dermatology. Photoluminescence analysis at room temperature (~25°C) shows that the synthesized CMS:Gd3+ phosphor emits narrowband UV-B light with a peak intensity at 314 nm. Comparative studies of the standard action spectrum of psoriasis with the emission spectrum of the CMS:Gd3+ phosphor show that the synthesized phosphor was the most suitable material for treating a variety of diseases, including psoriasis, vitiligo, type-1 diabetes, dental disease, sleep and mood disorders, and other skin diseases.

Keywords: akermanite; phosphor; photoluminescence; skin diseases; solid-state route; ultraviolet radiation.

MeSH terms

  • Humans
  • Ions / chemistry
  • Psoriasis* / radiotherapy
  • Rejuvenation*
  • Ultraviolet Rays

Substances

  • Glass ceramics
  • Ions