Retrospective Evaluation of Mycoplasma genitalium Prevalence and Macrolide Resistance in a Study Cohort of Pregnant Women in Birmingham, AL, From 1997 to 2001

Sex Transm Dis. 2023 Oct 1;50(10):642-644. doi: 10.1097/OLQ.0000000000001843. Epub 2023 Jul 1.

Abstract

In a prospective study conducted in 2020 to 2021, macrolide resistance-associated mutations were found in 41% of pregnant persons in Birmingham, AL, with Mycoplasma genitalium detected. We retrospectively evaluated M. genitalium in 203 pregnant persons participating in a study conducted in 1997 to 2001 in Birmingham and adjacent areas and found a prevalence of 11% (95% confidence interval, 6.9%-15.7%), but no macrolide resistance-associated mutations.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Drug Resistance, Bacterial / genetics
  • Female
  • Humans
  • Macrolides / pharmacology
  • Mycoplasma Infections* / drug therapy
  • Mycoplasma Infections* / epidemiology
  • Mycoplasma genitalium* / genetics
  • Pregnancy
  • Pregnant Women
  • Prevalence
  • Prospective Studies
  • Retrospective Studies

Substances

  • Anti-Bacterial Agents
  • Macrolides