CRISPR enables heritable genome editing in planta

Tofazzal Islam; Shamfin Hossain Kasfy

doi:10.1016/j.tig.2023.06.009

CRISPR enables heritable genome editing in planta

Trends Genet. 2023 Sep;39(9):646-648. doi: 10.1016/j.tig.2023.06.009. Epub 2023 Jul 8.

Authors

Tofazzal Islam¹, Shamfin Hossain Kasfy²

Affiliations

¹ Institute of Biotechnology and Genetic Engineering (IBGE), Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, Bangladesh. Electronic address: tofazzalislam@bsmrau.edu.bd.
² Institute of Biotechnology and Genetic Engineering (IBGE), Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, Bangladesh.

PMID: 37429772
DOI: 10.1016/j.tig.2023.06.009

Abstract

Recent exciting developments in clustered regularly interspaced short palindromic repeats (CRISPR)-based genome editing showcase its potential to rapidly and efficiently edit genomes in planta, eliminating long processes of tissue culture and extensive breeding for crop improvement. These new methods offer heritable transgene-free edits in one generation, making them an attractive option for improving commercially important crops.

Keywords: crop improvement; grafting; mobile CRISPR construct; speed breeding; viral vectors.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

CRISPR-Cas Systems* / genetics
Clustered Regularly Interspaced Short Palindromic Repeats / genetics
Gene Editing*
Genome, Plant / genetics
Plant Breeding