Annular and acral/facial dyskeratotic paraneoplastic disorders

Clin Dermatol. 2023 May-Jun;41(3):396-404. doi: 10.1016/j.clindermatol.2023.07.008. Epub 2023 Jul 7.

Abstract

Annular and acral/facial dyskeratotic paraneoplastic disorders are inflammatory dermatoses that occur in association with distant cancers but are not precursors, extensions, or metastases of them. There are four classical entities under this rubric: two gyrate entities, erythema annulare centrifugum and erythema gyratum repens, and two acral/facial dyskeratotic entities, acrokeratosis paraneoplastic (Bazex syndrome) and tripe palms. Each of these entities may also occur in association with another etiopathogenesis and may present either as a classical entity or as a barely recognizable disease. We discuss these entities, their associated causes, and their differential diagnoses in turn.

MeSH terms

  • Erythema / etiology
  • Humans
  • Paraneoplastic Syndromes* / diagnosis
  • Paraneoplastic Syndromes* / etiology
  • Skin / pathology
  • Skin Diseases, Genetic* / pathology
  • Skin Neoplasms* / complications
  • Skin Neoplasms* / pathology