Hybrid porous material supported in a cellulose acetate polymeric membrane for the direct immersion thin-film microextraction of parabens in water

Silindokuhle Jakavula; Azile Nqombolo; Anele Mpupa; Jianwei Ren; Philiswa Nosizo Nomngongo

doi:10.1016/j.chroma.2023.464187

Hybrid porous material supported in a cellulose acetate polymeric membrane for the direct immersion thin-film microextraction of parabens in water

J Chromatogr A. 2023 Aug 30:1705:464187. doi: 10.1016/j.chroma.2023.464187. Epub 2023 Jul 1.

Authors

Silindokuhle Jakavula¹, Azile Nqombolo², Anele Mpupa¹, Jianwei Ren³, Philiswa Nosizo Nomngongo⁴

Affiliations

¹ Department of Chemical Sciences, University of Johannesburg, Doornfontein Campus, P.O. Box 17011, Johannesburg 2028, South Africa; Department of Science and Innovation-National Research Foundation South African Research Chair Initiative (DSI-NRF SARChI) in Nanotechnology for Water, University of Johannesburg, Doornfontein 2028, South Africa.
² Department of Pure and Applied Chemistry, University of Fort Hare, Alice 5700, South Africa.
³ Department of Mechanical Engineering Science, University of Johannesburg, Cnr Kingsway and University Roads, Auckland Park, Johannesburg 2092, South Africa.
⁴ Department of Chemical Sciences, University of Johannesburg, Doornfontein Campus, P.O. Box 17011, Johannesburg 2028, South Africa; Department of Science and Innovation-National Research Foundation South African Research Chair Initiative (DSI-NRF SARChI) in Nanotechnology for Water, University of Johannesburg, Doornfontein 2028, South Africa; Department of Science and Innovation /Mintek Nanotechnology Innovation Centre, University of Johannesburg, Doornfontein 2028, South Africa. Electronic address: pnnomngongo@uj.ac.za.

PMID: 37419016
DOI: 10.1016/j.chroma.2023.464187

Abstract

A simple and sensitive direct immersion thin-film microextraction (DI-TFME) method based on MIL-101(Cr) modified with carbon nanofibers supported in cellulose acetate (CA-MIL-101(Cr)@CNFs) polymeric membrane was developed for the extraction and preconcentration of parabens in environmental water samples. A high-performance liquid chromatography-diode array detector (HPLC-DAD) was used for the determination and quantification of methylparaben (MP) and propylparaben (PP). The factors affecting the DI-TFME performance were investigated using central composite design (CCD). The linearity of the DI-TFME/HPLC-DAD method obtained under optimal conditions was 0.04-0.04-500 µg/L with a correlation coefficient (R²) greater than 0.99, respectively. The limits of detection (LOD) and quantification (LOQ) for methylparaben were 11 ng/L and 37 ng/L; for propylparaben, they were 13 ng/L and 43 ng/L, respectively. The enrichment factors were 93.7 and 123 for methylparaben and propylparaben. The intraday (repeatability) and interday (reproducibility) precisions expressed as relative standard deviations (%RSD) were less than 5%. Furthermore, the DI-TFME/HPLC-DAD method was validated using real water samples spiked with known concentrations of the analytes. The recoveries ranged from 91.5 to 99.8%, and intraday and interday trueness values were less than ±15%. The DI-TFME/HPLC-DAD approach was effectively used for the preconcentration and quantification of parabens in river water and wastewater samples.

Keywords: CA-MIL-101(Cr)@CNFs membrane; Direct immersion-thin film microextraction; Methylparaben; Polymer membranes; Propylparaben.

MeSH terms

Chromatography, High Pressure Liquid / methods
Immersion
Limit of Detection
Parabens* / analysis
Porosity
Reproducibility of Results
Water*

Substances

Water
propylparaben
methylparaben
Parabens
MIL-101
acetylcellulose