Advances in mRNA vaccines for viral diseases

Yukai Huang; Xuerui Zhu; Xiao Guo; Yuancheng Zhou; Dongying Liu; Jingrui Mao; Yongai Xiong; Youcai Deng; Xinghong Gao

doi:10.1002/jmv.28924

Advances in mRNA vaccines for viral diseases

J Med Virol. 2023 Jul;95(7):e28924. doi: 10.1002/jmv.28924.

Authors

Yukai Huang¹, Xuerui Zhu¹, Xiao Guo¹, Yuancheng Zhou², Dongying Liu¹, Jingrui Mao¹, Yongai Xiong³, Youcai Deng⁴, Xinghong Gao^{1

5}

Affiliations

¹ Department of Microbiology, School of Basic Medicine, Zunyi Medical University, Zunyi, Guizhou, China.
² Livestock and Poultry Biological Products Key Laboratory of Sichuan Province, Sichuan Animal Science Academy, Chengdu, China.
³ Department of Pharmaceutics, School of Pharmacy, Zunyi Medical University, Zunyi, Guizhou, China.
⁴ Department of Hematology, College of Pharmacy, Army Medical University (Third Military Medical University), Chongqing, China.
⁵ Provincial Department of Education, Key Laboratory of Infectious Disease & Bio-Safety, Zunyi Medical University, Zunyi, Guizhou, China.

PMID: 37417396
DOI: 10.1002/jmv.28924

Abstract

Since the onset of the pandemic caused by severe acute respiratory syndrome coronavirus 2, messenger RNA (mRNA) vaccines have demonstrated outstanding performance. mRNA vaccines offer significant advantages over conventional vaccines in production speed and cost-effectiveness, making them an attractive option against other viral diseases. This article reviewed recent advances in viral mRNA vaccines and their delivery systems to provide references and guidance for developing mRNA vaccines for new viral diseases.

Keywords: delivery systems; mRNA vaccines; viral diseases.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

COVID-19* / prevention & control
Humans
Pandemics
SARS-CoV-2 / genetics
Viral Vaccines* / genetics
Virus Diseases*
mRNA Vaccines

Substances

mRNA Vaccines
Viral Vaccines