Segmentation of In vitro Fertilization with High-intensity Focused Ultrasound in Repeated Implantation Failure with Adenomyosis

Pei-Hsiu Yu; Yu-Hsien Wu; Ta-Sheng Chen; Tsung-Cheng Kuo; Meng-Hsing Wu

doi:10.4103/gmit.gmit_95_22

Segmentation of In vitro Fertilization with High-intensity Focused Ultrasound in Repeated Implantation Failure with Adenomyosis

Gynecol Minim Invasive Ther. 2023 Apr 25;12(2):109-112. doi: 10.4103/gmit.gmit_95_22. eCollection 2023 Apr-Jun.

Authors

Pei-Hsiu Yu^{1

2}, Yu-Hsien Wu¹, Ta-Sheng Chen¹, Tsung-Cheng Kuo², Meng-Hsing Wu^{1

2

3}

Affiliations

¹ Department of Obstetrics and Gynecology, College of Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan.
² Department of Obstetrics and Gynecology, Kuo General Hospital, Tainan, Taiwan.
³ Department of Obstetrics and Gynecology, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Abstract

Adenomyosis is a complex issue in reproductive-age women not only on worsening of quality of life due to severe dysmenorrhea or heavy menstrual bleeding but also on the impact of infertility. A 39-year-old female, gravida 0 para 0, with a history of bilateral ovarian endometrioma post laparoscopic surgery presented to our hospital due to suspected deep infiltrative endometriosis (DIE), adenomyosis, and repeated implantation failure. Initially, gonadotropin-releasing hormone analog treatment for DIE with progestin-primed ovarian stimulation protocol was arranged. Four D5 blastocysts were obtained and freezed. Two frozen embryo transfer were performed after ultrasound-guided high-intensity focused ultrasound (USgHIFU) treatment of adenomyosis. She later had a dichorionic diamniotic twin pregnancy, and two healthy newborns were delivered by Cesarean section at gestational age of 35 weeks due to antepartum hemorrhage with placenta previa and preeclampsia. In conclusion, USgHIFU can be a potential treatment option in segmented in vitro fertilization in future.

Keywords: Adenomyosis; in vitro fertilization; segmentation; ultrasound-guided high-intensity focused ultrasound.

Publication types

Case Reports