The Role of Drug-Coated Balloon in Haemodialysis Arteriovenous Fistula Stenosis Management

Cardiovasc Intervent Radiol. 2023 Sep;46(9):1144-1153. doi: 10.1007/s00270-023-03497-9. Epub 2023 Jul 6.

Abstract

Arteriovenous fistula (AVF) stenosis is a common problem leading to dialysis access dysfunction. The conventional balloon (CB) is the most commonly used device during angioplasty but suffers from poor durability of results due to neointimal hyperplasia-mediated recurrence. The drug-coated balloon (DCB) is an adjunct to balloon angioplasty that reduces neointimal hyperplasia, thereby improving post-angioplasty patency. Despite the heterogeneity of DCB clinical trials to date, the evidence suggests that DCBs of different brands are not necessarily equal, and that patient selection, adequate lesion preparation and proper DCB procedural technique are important to realize the benefit of DCB angioplasty.

Keywords: Arteriovenous fistula; Drug-coated balloon; Drug-eluting balloon; Haemodialysis; Paclitaxel-coated balloon; Stenosis.

Publication types

  • Review

MeSH terms

  • Angioplasty, Balloon* / methods
  • Arteriovenous Fistula* / diagnostic imaging
  • Arteriovenous Fistula* / therapy
  • Arteriovenous Shunt, Surgical*
  • Cardiovascular Agents*
  • Coated Materials, Biocompatible
  • Constriction, Pathologic
  • Graft Occlusion, Vascular / diagnostic imaging
  • Graft Occlusion, Vascular / therapy
  • Humans
  • Hyperplasia
  • Paclitaxel
  • Renal Dialysis
  • Time Factors
  • Treatment Outcome
  • Vascular Access Devices*
  • Vascular Patency

Substances

  • Cardiovascular Agents
  • Coated Materials, Biocompatible
  • Paclitaxel