Cutaneous Sarcoidosis: A Differential Diagnosis to Consider in Undiagnosed Skin Lesions

Cureus. 2023 Jun 1;15(6):e39852. doi: 10.7759/cureus.39852. eCollection 2023 Jun.

Abstract

The presentation of sarcoidosis varies depending on the organs involved. Cutaneous sarcoidosis usually presents with other organ involvement, but isolated presentation is possible. However, diagnosing isolated cutaneous sarcoidosis can be challenging in resource-poor countries, particularly where sarcoidosis is relatively uncommon, since cutaneous sarcoidosis usually does not cause troublesome symptoms. We present a case of cutaneous sarcoidosis in an elderly female who had been suffering from skin lesions for nine years. The diagnosis was made after the appearance of lung involvement, which raised the suspicion of sarcoidosis and prompted a skin biopsy. The patient was then treated with systemic steroids and methotrexate, and her lesions improved shortly thereafter. This case highlights the importance of considering sarcoidosis as a possible cause of undiagnosed, refractory cutaneous lesions.

Keywords: cutaneous sarcoidosis; lung fibrosis; noncaseating granuloma; refractory skin lesions; skin biopsy.

Publication types

  • Case Reports