Light alkenes are the key building blocks in the chemical industry. As a propene on-purpose production technology, propane dehydrogenation has drawn particular attention due to the growing demand for propene and the discovery of large reserves of shale gas. The development of highly active and stable propane dehydrogenation catalysts is significant in the world-wide research field. Supported platinum-based catalysts are widely studied for propane dehydrogenation. This article reviews the developments of platinum-based catalysts in propane dehydrogenation, particularly focusing on the influence of the promoter effect and support effect on the structure and catalytic performance and especially on how promoters and supports enable Pt to form highly dispersed and stable active sites. At the end, we propose the prospective research directions of propane dehydrogenation.