[Three cases of acute chlorfenapyr poisoning]

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2023 Jun 20;41(6):461-462. doi: 10.3760/cma.j.cn121094-20220307-00113.
[Article in Chinese]

Abstract

This paper reported 3 cases of poisoning caused by chlorfenagyr. Chlorfenapyr poisoning has gradually increased in clinical practice. The early stage after poisoning is digestive tract symptoms, followed by sweating, high fever, changes in consciousness, changes in myocardial enzymology, etc. Its main mechanism of intoxication is uncoupling oxidative phosphorylation. Since there is no specific antidote after poisoning, the fatality rate of chlorfenapyr poisoning remains high. The therapeutic measures are early gastrointestinal decontamination, symptomatic and supportive treatments, and early blood purification may be an effective treatment.

本文报道3例虫螨腈中毒病例。虫螨腈中毒病例在临床上呈增多趋势,患者中毒早期表现为消化道症状,后逐渐出现大汗、高热、意识改变、心肌酶改变等,其中毒机制为解耦联氧化磷酸化。由于无特效解毒药,虫螨腈中毒病死率较高,治疗方法包括胃肠道毒物清除及对症支持治疗,早期血液净化效果较好。.

Keywords: Blood purification; Chlorfenapyr; Insecticides; Poisoning.

Publication types

  • English Abstract

MeSH terms

  • Gastrointestinal Tract
  • Humans
  • Insecticides*
  • Poisoning* / diagnosis
  • Pyrethrins*

Substances

  • chlorfenapyr
  • Pyrethrins
  • Insecticides