The Diabetes-Heart Disease Connection: Recent Discoveries and Implications

Curr Probl Cardiol. 2023 Nov;48(11):101923. doi: 10.1016/j.cpcardiol.2023.101923. Epub 2023 Jul 1.

Abstract

Diabetes and heart disease are 2 prevalent and interconnected conditions with a significant global burden. Understanding the relationship between diabetes and heart disease is crucial for effective management and prevention strategies. This article provides an overview of the 2 conditions, highlighting their types, risk factors, and global prevalence. Recent research findings establish a strong correlation between diabetes and various aspects of cardiovascular health, including coronary artery disease, heart failure, and stroke. Mechanisms such as insulin resistance, inflammation, and oxidative stress contribute to the interplay between diabetes and heart disease. The implications for clinical practice underscore the importance of early detection, risk assessment, and comprehensive management of both conditions. Lifestyle modifications, such as diet, exercise, and weight management, are essential interventions. Pharmacological interventions, including antidiabetic drugs and cardiovascular medications, play a crucial role in treatment. Managing diabetes and heart disease simultaneously poses challenges that require interdisciplinary collaboration among endocrinologists, cardiologists, and primary care physicians. Ongoing research explores personalized medicine and targeted therapies as potential future directions. Continued research and awareness are paramount to mitigate the impact of the diabetes-heart disease connection and improve patient outcomes.

Publication types

  • Review

MeSH terms

  • Cardiovascular Agents*
  • Diabetes Mellitus*
  • Heart Diseases*
  • Humans
  • Hypoglycemic Agents / therapeutic use
  • Risk Factors

Substances

  • Hypoglycemic Agents
  • Cardiovascular Agents