Nitrates in industrial and traditional tomato paste from Arsenjan City, Iran: a health risk assessment study

Int J Environ Health Res. 2024 Mar;34(3):1638-1651. doi: 10.1080/09603123.2023.2231367. Epub 2023 Jul 3.

Abstract

A comprehensive approach was used for the first time to measure NO3- risk in tomato paste consumption; besides a robust deterministic and probabilistic method was used. The mean levels of NO3- in homemade and industrial tomato paste were 7.36 mg/kg and 43.69 mg/kg, respectively. The Monte Carlo simulation confirmed that these values were below normal levels (HQ less than 1). The sensitivity analysis displayed that FIR was the main factor affecting the risk to human health in both groups. The interactive plot demonstrated the interaction between C and IR for children and adults in both types of tomato paste. This study concludes that NO3- ingestion due to tomato paste consumption poses no significant health risk. However, considering that food and water constitute the primary sources of NO3- intake, continuous monitoring is recommended due to potential health risks associated with excessive NO3- consumption, including certain forms of cancer.

Keywords: Monte carlo simulation; Nitrate; Sobol sensitivity analysis; food safety; health risk assessment.

MeSH terms

  • Adult
  • Child
  • Environmental Monitoring
  • Food
  • Humans
  • Iran
  • Nitrates / analysis
  • Risk Assessment
  • Solanum lycopersicum*
  • Water Pollutants, Chemical* / analysis
  • Water Pollutants, Chemical* / toxicity

Substances

  • Nitrates
  • Water Pollutants, Chemical