Encapsulation into hyaluronic acid-based nanogels improves the selectivity index of the snake cathelicidin Ab-Cath

Nanomedicine. 2023 Aug:52:102694. doi: 10.1016/j.nano.2023.102694. Epub 2023 Jun 30.

¹ Department of Infectious Diseases, Leiden University Medical Center, 2300 RC Leiden, the Netherlands. Electronic address: M.E.van_Gent@lumc.nl.
² Center for Biopharmaceuticals and Biobarriers in Drug Delivery (BioDelivery), Department of Pharmacy, Faculty of Health and Medical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark.
³ Department of Infectious Diseases, Leiden University Medical Center, 2300 RC Leiden, the Netherlands.
⁴ Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, the Netherlands.
⁵ Electron Microscopy Facility, Department of Cell and Chemical Biology, Leiden University Medical Center, 2300 RC Leiden, the Netherlands.
⁶ Department of Immunology, Leiden University Medical Center, 2300 RC Leiden, the Netherlands.

No abstract available

Keywords: AMR infection; Antimicrobial peptide Ab-Cath; Drug delivery; Lyophilization method; Nanogel.

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