Unusual presentation of Pott disease and diagnostic challenges in a resource-limited setting: a case report

J Med Case Rep. 2023 Jul 2;17(1):276. doi: 10.1186/s13256-023-04015-8.

Abstract

Background: Pott disease is rare and responsible for only 1%-2% of all tuberculosis cases. It poses diagnostic challenges in resource-limited settings due to unusual presentation and limited investigative capacity, resulting in debilitating sequelae if diagnosed late.

Case presentation: We present a case of severe Pott disease of the lumbar spine, with a large paravertebral abscess tracking down to the gluteal region in a 27-year-old Black African Ugandan woman living with human immunodeficiency virus, whose main complaint was right lower abdominal pain. She was initially misdiagnosed from the peripheral clinics as a case of lumbago and later with a psoas abscess. The diagnosis of severe Pott disease was established at the regional referral hospital following an abdominal computed tomography scan, and the patient was appropriately initiated on anti-tuberculosis drugs. However, only abscess drainage and provision of a lumbar corset were possible, with no neurosurgical intervention done on the spine due to financial constraints. Clinical review at 2, 6, and 12 months revealed improvement.

Conclusions: Pott disease may present with non-specific symptoms such as abdominal pain resulting from pressure effects of an expansile cold abscess. This, coupled with limited diagnostic capacity in resource-limited settings; results in significant morbidity and possible mortality. Hence, there is need to train clinicians to increase their index of suspicion and equip health units with basic radiological equipment, such as x-ray, for timely detection and subsequent management of Pott disease.

Keywords: Case report; Extrapulmonary tuberculosis; Paravertebral abscess; Pott disease; TB spondylodiscitis.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Pain / etiology
  • Adult
  • Antitubercular Agents
  • Female
  • Humans
  • Lumbar Vertebrae
  • Psoas Abscess* / diagnosis
  • Psoas Abscess* / therapy
  • Tuberculosis, Spinal* / diagnostic imaging
  • Tuberculosis, Spinal* / therapy

Substances

  • Antitubercular Agents