Brain activity differences between susceptible and non-susceptible populations under visually induced motion sickness based on sensor-space and source-space analyses

Lu Zhou; Haixu Hu; Bing Qin; Qiaoqiao Zhu; Zhiyu Qian

doi:10.1016/j.brainres.2023.148474

Brain activity differences between susceptible and non-susceptible populations under visually induced motion sickness based on sensor-space and source-space analyses

Brain Res. 2023 Sep 15:1815:148474. doi: 10.1016/j.brainres.2023.148474. Epub 2023 Jun 29.

Authors

Lu Zhou¹, Haixu Hu², Bing Qin¹, Qiaoqiao Zhu³, Zhiyu Qian⁴

Affiliations

¹ Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China; Key Laboratory of Multimodal Brain-Computer Precision Drive Ministry of Industry and Information Technology, Nanjing 210016, China; Key Laboratory of Digital Medical Equipment and Technology of Jiangsu Province, Nanjing 210016, China.
² Sports Training Academy, Nanjing Sport Institute, Nanjing 210016, China.
³ Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China; Key Laboratory of Multimodal Brain-Computer Precision Drive Ministry of Industry and Information Technology, Nanjing 210016, China; Key Laboratory of Digital Medical Equipment and Technology of Jiangsu Province, Nanjing 210016, China. Electronic address: zqq@nuaa.edu.cn.
⁴ Department of Biomedical Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China; Key Laboratory of Multimodal Brain-Computer Precision Drive Ministry of Industry and Information Technology, Nanjing 210016, China; Key Laboratory of Digital Medical Equipment and Technology of Jiangsu Province, Nanjing 210016, China. Electronic address: zhiyu_q@163.com.

PMID: 37393010
DOI: 10.1016/j.brainres.2023.148474

Abstract

The neural mechanisms underlying visually induced motion sickness (VIMS) in different susceptible populations are unclear, as it is not clear how brain activity changes in different susceptible populations during the vection section (VS). This study aimed to analyze the brain activity changes in different susceptible populations during VS. Twenty subjects were included in this study and divided into the VIMS-susceptible group (VIMSSG) and VIMS-resistant group (VIMSRG) based on a motion sickness questionnaire. 64-channel electroencephalogram (EEG) data from these subjects during VS were collected. The brain activities during VS for VIMSSG and VIMSRG were analyzed with time-frequency based sensor-space analysis and EEG source imaging based source-space analysis. Under VS, delta and theta energies were significantly increased in VIMSSG and VIMSRG, while alpha and beta energies were only significantly increased in VIMSRG. Also, the superior and middle temporal were activated in VIMSSG and VIMSRG, while lateral occipital, supramarginal gyrus, and precentral gyrus were activated only in VIMSSG. The spatiotemporal differences in brain activity observed between VIMSSG and VIMSRG may be attributed to the different susceptibility of participants in each group and the different severity of MS symptoms experienced. Long-term vestibular training can effectively improve the ability of anti-VIMS. The knowledge gained from this study helps advance understanding of the neural mechanism of VIMS in different susceptible populations.

Keywords: Electroencephalogram (EEG); Susceptibility; VIMS-resistant group (VIMSRG); VIMS-susceptible group (VIMSSG); Visual induced motion sickness (VIMS).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Electroencephalography
Humans
Motion Sickness*
Occipital Lobe