An Intriguing Case of Gynecomastia in an Elderly Male as the Initial Presentation of Graves' Disease: A Case Report

Cureus. 2023 May 21;15(5):e39286. doi: 10.7759/cureus.39286. eCollection 2023 May.

Abstract

Gynecomastia is the proliferation of fibroglandular tissue in the male breast due to an altered hormonal milieu between the inhibitory effect of androgens and the stimulatory effect of estrogens on the breast tissue causing feminization of the male breast. Physiological causes are more common along with a few pathological conditions leading to gynecomastia in the male population. Of these varied etiologies, thyrotoxicosis is one of the notable causes, though it is very rare in the elderly population. Gynecomastia as the initial presentation of Graves' disease that too in an elderly age group is very rare with very few cases reported in the literature. Here, we present a case of a 62-year-old male presenting with gynecomastia, who after a detailed evaluation, was diagnosed to have Graves' disease.

Keywords: elderly male; graves’ disease; gynecomastia; shbg(sexhormone binding globulin); testosterone.

Publication types

  • Case Reports