Severe form of lymphocutaneous sporotrichosis: a case report

Rev Inst Med Trop Sao Paulo. 2023 Jun 23:65:e41. doi: 10.1590/S1678-9946202365041. eCollection 2023.

Abstract

Sporotrichosis is the most frequent subcutaneous mycosis in Latin America. It is caused by species of the genus Sporothrix. Infection in humans occurs through the entry of the fungus into the skin. Zoonotic outbreaks involving cats in the transmission of the disease have been frequently reported. The lymphocutaneous form is the most commonly observed and the upper limbs are the most affected sites. We report a case of a 64-year-old healthy female patient with a lymphocutaneous form with rapid progression of lesions, which was refractory to initial treatment with itraconazole. Treatment with liposomal amphotericin B was performed with a satisfactory resolution, but aesthetic and functional sequelae in the left upper limb were installed.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Disease Outbreaks
  • Female
  • Humans
  • Itraconazole / therapeutic use
  • Middle Aged
  • Sporothrix*
  • Sporotrichosis* / diagnosis
  • Sporotrichosis* / drug therapy

Substances

  • Itraconazole
  • Antifungal Agents