Green Routes for Bio-Fabrication in Biomedical and Pharmaceutical Applications

Pharmaceutics. 2023 Jun 15;15(6):1744. doi: 10.3390/pharmaceutics15061744.

Abstract

In the last decade, significant advances in nanotechnologies, rising from increasing knowledge and refining of technical practices in green chemistry and bioengineering, enabled the design of innovative devices suitable for different biomedical applications. In particular, novel bio-sustainable methodologies are developing to fabricate drug delivery systems able to sagely mix properties of materials (i.e., biocompatibility, biodegradability) and bioactive molecules (i.e., bioavailability, selectivity, chemical stability), as a function of the current demands for the health market. The present work aims to provide an overview of recent developments in the bio-fabrication methods for designing innovative green platforms, emphasizing the relevant impact on current and future biomedical and pharmaceutical applications.

Keywords: drug delivery; electro fluid dynamics; green chemistry; nanoparticles; natural polymers.

Publication types

  • Review

Grants and funding

This work was supported by the Foundation of Sardinia (Bando Fondazione di Sardegna—2018–2020 e 2021—Progetti di ricerca di base dipartimentali”; Grant numbers J89J21015120005. AFOSR 3DNEUROGLIA FA9550-18-1-0255, MSCA-ITN-2020-ASTROTECH (GA956325).