Rarely Encountered Gram-Negative Rods and Lung Transplant Recipients: A Narrative Review

Microorganisms. 2023 May 31;11(6):1468. doi: 10.3390/microorganisms11061468.

Abstract

The respiratory tract of lung transplant recipients (LTR) is likely to be colonized with non-fermentative Gram-negative rods. As a consequence of the improvements in molecular sequencing and taxonomy, an increasing number of bacterial species have been described. We performed a review of the literature of bacterial infections in LTR involving non-fermentative Gram-negative rods with exclusion of Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Achromobacter spp. and Burkholderia spp. Overall, non-fermenting GNR were recovered from 17 LTR involving the following genera: Acetobacter, Bordetella, Chryseobacterium, Elizabethkinga, Inquilinus, and Pandoraea. We then discuss the issues raised by these bacteria, including detection and identification, antimicrobial resistance, pathogenesis, and cross-transmission.

Keywords: acetobacter; bordetella; chryseobacterium; elizabethkinga; inquilinus; lung transplant recipient; pandoraea.

Publication types

  • Review

Grants and funding

This research received no external funding.